Matthew Broderick
Hubble (voice)
Donald Faison
Wilson (voice)
Cheech Marin
The Greater Dane's Henchman (voice)
Brittany Murphy
Nelly (voice)
Vanessa Redgrave
The Greater Dane (voice)
Delta Burke
Barbara Ann (voice)
Brittany Moldowan
Connie Fleming
George Touliatos
Mr. Leone
Ben Immanuel
Wilson's Dad (as Benjamin Ratner)
Peter Flemming
Wilson's Other Dad
Paul Vogt
Bob the Dog Catcher (as Paul C. Vogt)
Brenda Crichlow
Mrs. Fleming (as Brenda M. Crichlow)
D. Harlan Cutshall
Mr. Fleming
Chaka White
Woman at the Pound
Nicola Anderson
Woman at the Pound
Mig Macario
Asian Dad (uncredited)
