Simon Baker
Roderick Blank
Winona Ryder
Death Nell / Gillian De Raisx (#101)
Leslie Bibb
Dr. Miranda Storm
Julie Bowen
Fiona Wormwood (#29)
Frances Fisher
Hope Hartlight (#80)
Marshall Bell
Victor Rose III
Sophie Monk
Cynthia Rose (#31)
Natassia Malthe
Bambi (#63)
Pollyanna McIntosh
Thumper (#64)
Jessica Kiper
Precious / Carlotta Valdes (#30)
Winter Ave Zoli
Alexis De Large (#37)
Cindy Pickett
Roderick's Mother
Candice Coke
Greta Samsa (#32)
Christopher Stapleton
Terry Fenchel (#71)
Retta
Ethel Walters (#100)
Amanda Walsh
Stewardess Kathleen
Bryan Okes
Buzzkilling Bodyguard
Zachary Gordon
Barbecue Brat
Skyler James Sandak
Roderick Blank Jr.
Nicole Bilderback
Dr. Mirabella Stone (#66)
Keram Malicki-Sánchez
Master Bitchslap
Siobhan Flynn
Esther Fenchel
Bryan Ross
Bachelor Party Buddy (as Brian Ross)
Greg Travis
Vulgar Newsstand Vendor
David Magidoff
Video Store Geek
Buckley Norris
Club Owner (as Buckley Francis Norris)
Tarek Bishara
Malcolm the Bartender (as Thom Bishops)
William Caploe
Barista Bill
Patrick Leo Holland
Wonderful Waiter
Ryan Cutrona
Officer Krupke
Cean Okada
Edwina Massey (#67)
Lauren Michelle Hill
Amberette
Annie Kehoe
Death Nell Wannabee
Kacie Borrowman
Vixen Blitzen (#69)
Elisha Skorman
Helena Hartford (uncredited)
